Cancer Types
Glioblastoma
Also known as: GBM, Grade IV astrocytoma, Glioblastoma multiforme
Definition
The most aggressive and common malignant primary brain tumor in adults, arising from glial cells and characterized by rapid growth and poor prognosis.
Detailed Explanation
Glioblastoma (GBM) is a Grade IV astrocytoma with median survival of 12-15 months despite aggressive treatment. Standard therapy includes maximal safe surgical resection, radiation, and temozolomide chemotherapy. The tumor infiltrates surrounding brain tissue, making complete removal impossible.