Side Effects
Myelosuppression
Also known as: Bone marrow suppression, Bone marrow depression
Definition
A decrease in bone marrow activity leading to reduced production of blood cells, commonly caused by chemotherapy.
Detailed Explanation
Myelosuppression results in low counts of red blood cells (anemia), white blood cells (neutropenia), and platelets (thrombocytopenia). This can cause fatigue, increased infection risk, and bleeding problems. Management includes growth factors, blood transfusions, dose adjustments, and infection prevention measures.