Oncology
Renal Cell Carcinoma
Also known as: Kidney cancer, RCC, Renal carcinoma
Definition
The most common type of kidney cancer in adults, originating from the lining of the kidney tubules.
Detailed Explanation
RCC accounts for about 90% of kidney cancers. Clear cell RCC is the most common subtype. Treatment depends on stage and includes surgery (nephrectomy), targeted therapy (TKIs like sunitinib), and immunotherapy combinations (nivolumab + ipilimumab or pembrolizumab + axitinib).