Cancer Types
Triple-Negative Breast Cancer
Also known as: TNBC
Definition
An aggressive breast cancer subtype that tests negative for estrogen receptors, progesterone receptors, and HER2 protein, representing about 10-15% of all breast cancers.
Detailed Explanation
Triple-negative breast cancer is called 'triple-negative' because the cancer cells don't have estrogen or progesterone receptors and also don't make too much of the protein called HER2. This makes it harder to treat because hormone therapy and HER2-targeted drugs are not effective. However, immunotherapy and chemotherapy show promise.