Immunotherapy
CAR T-Cell Therapy
Also known as: CAR-T therapy, Chimeric antigen receptor therapy
Definition
A personalized immunotherapy where a patient's T cells are engineered to recognize and attack cancer cells.
Detailed Explanation
CAR T (Chimeric Antigen Receptor T-cell) therapy involves collecting a patient's T cells, genetically modifying them to express cancer-targeting receptors, expanding them in the lab, and infusing them back. Approved for certain blood cancers like ALL, DLBCL, and multiple myeloma. Can cause severe side effects like cytokine release syndrome but may achieve long-term remissions.