Side Effects
Immune-Related Pneumonitis
Also known as: Checkpoint inhibitor pneumonitis, ILD (interstitial lung disease)
Definition
Inflammation of the lungs caused by immunotherapy, presenting with cough, shortness of breath, and chest pain.
Detailed Explanation
Pneumonitis occurs in 3-5% of patients receiving checkpoint inhibitors and can be serious. Symptoms include new or worsening cough, shortness of breath, and chest discomfort. Diagnosis requires chest imaging and sometimes bronchoscopy. Treatment involves stopping immunotherapy and using corticosteroids for moderate to severe cases.