Treatment Procedures
Tumor Infiltrating Lymphocyte Therapy
Also known as: TIL therapy, Adoptive cell therapy, Tumor infiltrating lymphocytes
Definition
A personalized cell therapy extracting immune cells from a patient's tumor, expanding them in the lab, and reinfusing them to fight cancer, particularly effective in melanoma.
Detailed Explanation
TIL therapy involves surgically removing a tumor piece, isolating lymphocytes that have naturally infiltrated it, growing billions of these cells in the lab, then giving them back to the patient after lymphodepleting chemotherapy. Response rates exceed 50% in melanoma.